ProSci

Mouse Irak3 Antibody

Product Code:
 
PSI-57-600
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in mouse kidney tissue lysates (35ug/lane).
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Western blot analysis in mouse kidney tissue lysates (35ug/lane).

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PSI-57-600-400ul400ul£626.00
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Further Information

Additional Names:
Interleukin-1 receptor-associated kinase 3, IRAK-3, IL-1 receptor-associated kinase M, IRAK-M, Irak3 {ECO:0000312|MGI:MGI:1921164}
Application Note:
For WB starting dilution is: 1:1000
Background:
Irak3 inhibits dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex.
Background References:
  • Turnis, M.E., et al. J. Immunol. 185(7):4223-4232(2010)
  • Hubbard, L.L., et al. J. Immunol. 184(11):6299-6308(2010)
  • Seki, M., et al. J. Immunol. 184(3):1410-1418(2010)
  • Lyn-Kew, K., et al. PLoS ONE(6), E11145 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This Mouse Irak3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 517-544 amino acids from the C-terminal region of mouse Irak3.
NCBI Gene ID #:
73914
NCBI Official Name:
Interleukin-1 receptor-associated kinase 3
NCBI Official Symbol:
Irak3
NCBI Organism:
Mus musculus
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
68 kDa
Protein Accession #:
Q8K4B2
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology,Signal Transduction
Swissprot #:
Q8K4B2
User NOte:
Optimal dilutions for each application to be determined by the researcher.