ProSci

Mouse Map3k3 Antibody

Product Code:
 
PSI-57-591
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in mouse liver tissue lysates (35ug/lane).
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Western blot analysis in mouse liver tissue lysates (35ug/lane).

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PSI-57-591-400ul400ul£626.00
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Further Information

Additional Names:
Mitogen-activated protein kinase kinase kinase 3, MAPK/ERK kinase kinase 3, MEK kinase 3, MEKK 3, Map3k3, Mekk3
Application Note:
For WB starting dilution is: 1:1000
Background:
Component of a protein kinase signal transduction cascade. Map3k3 mediates activation of the NF-kappa-B, AP1 and DDIT3 transcriptional regulators.
Background References:
  • Zhang, J., et al. J. Immunol. 185(6):3554-3563(2010)
  • Yu, L., et al. Cancer Res. 70(4):1334-1343(2010)
  • Sun, W., et al. Cell. Signal. 21(10):1488-1494(2009)
  • Retting, K.N., et al. Development 136(7):1093-1104(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This Mouse Map3k3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 228-257 amino acids from the Central region of mouse Map3k3.
NCBI Gene ID #:
26406
NCBI Official Name:
Mitogen-activated protein kinase kinase kinase 3
NCBI Official Symbol:
Map3k3
NCBI Organism:
Mus musculus
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
71 kDa
Protein Accession #:
Q61084
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology,Signal Transduction
Swissprot #:
Q61084
User NOte:
Optimal dilutions for each application to be determined by the researcher.