NSJ Bioreagents

Cathepsin L Antibody

Product Code:
 
NSJ-R30013
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Mouse
Antibody Isotype:
 
Mouse IgG1
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
CP-L14, aka 33/2
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunohistochemistry- Frozen Section (IHC-F)
  • Western Blot (WB)
Storage:
 
After reconstitution, the Cathepsin L antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.
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Western blot testing of human A549 cell lysate with Cathepsin L antibody. Expected molecular weight: 38-41 kDa with multiple smaller processed/active forms.
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Western blot testing of human A549 cell lysate with Cathepsin L antibody. Expected molecular weight: 38-41 kDa with multiple smaller processed/active forms.

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NSJ-R30013-100ug100 ug£535.00
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Further Information

Application Details :
Western blot: 2ug/ml,Immunohistochemistry (Frozen): 4ug/ml-formalin/acetone fixed tissues
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the Cathepsin L antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Cathepsin L is a lysosomal cysteine proteinase with a major role in intracellular protein catabolism. It also shows the most potent collagenolytic and elastinolytic activity in vitro of any of the cathepsins. Cathepsin L has been implicated in pathologic processes including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. Human liver cathepsin L consists of a heavy chain of about 25 kD and a light chain of about 5 kD. The gene is mapped to 9q21-q22. Cathepsin L is required for endothelial progenitor cell-induced neovascularization.
Format :
Ascites
Formulation :
0.5mg/ml with 1% BSA and 0.01% sodium azide if reconstituted with 0.2ml sterile 1XPBS
Gene ID #:
1514
Immunogen:
Procathepsin L isolated from the human lung cancer cell line EPLC 32M1 was used as the immunogen for this Cathepsin L antibody.
Limitation:
This Cathepsin L antibody is available for research use only.
Purity:
Ascites
Species Reactivity :
Human, mouse, rat