NSJ Bioreagents

SDHC Antibody

Product Code:
 
NSJ-R30937
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
 
After reconstitution, the SDHC antibody can be stored for up to one month at 40. For long-term, aliquot and store at -200. Avoid repeated freezing and thawing.
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Western blot testing of SDHC antibody and Lane 1: rat liver; 2: HeLa; 3: Jurkat cell lysate
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IHC-P: SDHC antibody testing of human gastric cancer tissue
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IHC-P: SDHC antibody testing of rat gastric tissue
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Western blot testing of SDHC antibody and Lane 1: rat liver; 2: mouse liver; 3: human HeLa cell lysate
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Western blot testing of SDHC antibody and Lane 1: rat liver; 2: HeLa; 3: Jurkat cell lysate
IHC-P: SDHC antibody testing of human gastric cancer tissue
IHC-P: SDHC antibody testing of rat gastric tissue
Western blot testing of SDHC antibody and Lane 1: rat liver; 2: mouse liver; 3: human HeLa cell lysate

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NSJ-R30937-100ug100 ug£535.00
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Further Information

Application Details :
Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml
Application Note:
The stated application concentrations are suggested starting amounts. Titration of the SDHC antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
The Succinate dehydrogenase complex, subunit C (SDHC), also called SDH3, gene contains 6 exons. Oostveen et al.(1995) found that in fact it was protein from the bovine SDHC/SDH3 gene (encoding 1 of the 2 integral membrane proteins) that complemented the hamster mutation. The authors localized the human SDH3 gene to the short arm of chromosome one, within 1 to 2 Mb from the centromere. Additionally, the authors stated that Southern analyses of human genomic DNA suggested that there are multiple SDH3 genes or pseudogenes. Elbehti-Green et al.(1998) confirmed the assignment of the SDHC gene to 1q21 by FISH. Baysal et al.(2004) described a family with PGL3 in which an 8,372-bp deletion in the SDHC gene was transmitted both maternally and paternally, without evidence of genomic imprinting.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
An amino acid sequence from the N-terminus of human Succinate dehydrogenase complex subunit C (KEEMERFWNKNIGSNR) was used as the immunogen for this SDHC antibody.
Limitation:
This SDHC antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human, Mouse, Rat
Uniprot #:
Q99643