Elabscience - Biological Research ELISA, Antibody and Protein Manufacturer for Life Science - Distributed in the UK and Europe by Caltag Medsystems

Gene Synthesis Service

Gene synthesis, sometimes known as DNA printing, is a method in synthetic biology used to create artificial genes. Based on solid-phase DNA synthesis, it differs from molecular cloning and polymerase chain reaction (PCR) in that it does not have to begin with preexisting DNA sequences. Therefore, it is possible to make a completely synthetic double-stranded DNA molecule with no apparent limits on either nucleotide sequence or size.

Advantages of Elabscience's Gene Synthesis Service:

• Short turn-around time.
• 100% sequence accuracy guarantee.
• Site directed mutagenesis service available.
• Covers any length or complexity.
• Free codon optimisation and free cloning into many standard vectors.
• Over 95% success rate with “No Gene, No Charge” policy. No hidden costs and no setup charges.

Peptide Synthesis Service

Elabscience's peptide synthesis service provides normal linear peptides, special long peptides, cyclic peptides, or modified peptides of different qualities and purity ranges. The quality can be from mg, g to kg and the purity covers crude, desalted, 70%, 75%, 80%, 85%, 90%, 95% and 98%.

Advantages of Elabscience's Peptide Synthesis Service:

• Up to 100aa peptide sequences can be synthesised.
• Variety of peptide modification services.
• Over 95% of synthesis success rate.
• Fastest peptide synthesis speed in the industry.
• All peptides are analysed by MS and HPLC.

Modifications Available:

• N-Terminal Modifications
• C-Terminal Modifications
• D-Amino Acids
• Unnatural/Unusual amino acids
• Fluorescence/Dye Labelling
• Stable isotope labelled peptides
• Pegylation
• Cyclic peptide
• Peptide conjugates

Applications:

• Antibody epitope mapping.
• Monoclonal and polyclonal antibody production.
• Non-quantitative enzyme-substrate studies.
• Biological effects of defined peptides.
• Blocking and competition assays of proteases.
• New techniques for separation by chromatography/electrophoresis.
• Immunisation and quantitative receptor-ligand interactions.
• Antibody-antigen interactions.
• ELISA standards for measuring titres of antibodies.
• Epitope mapping structure, dynamics, and folding of peptides and proteins via NMR.

Custom Protein Services

Yeast Expression System Protein Service

Yeast protein expression system is the most economical eukaryotic expression system for both secretion and intracellular expression. It is ideally suitable for large-scale production of recombinant eukaryotic proteins.

Elabscience’s Yeast Protein Expression System Service start with gene analysis, followed by subcloning, screening of expression strains and small amount protein expression. According to your project, they can offer the target protein in large scale (1~5L or 1~30L). Results of each service will be delivered with their identification reports to keep you informed of the progress. You can order every single service or any combination of these services according to your project program.

Advantages of Elabscience's Yeast Expression System Protein Service:

• Proprietary Technologies: Elabscience's advanced protein platform considers promoters, optimal copies of vector per cell, inducibility, signal peptides, and cellular location, which are essential for high-level recombinant protein production.
• Humanised antibody production: Elabscience has developed a platform that produces humanised antibodies in a yeast expression system. The similarity between the yeast and mammalian system for recombinant antibody expression enables Elabscience to reduce the high cost associated with manufacturing recombinant antibodies in mammalian expression system.
• Streamlined Services: Elabscience can take your project directly from gene synthesis, to the downstream contents including recombinant protein expression, antibody production, and assay development.

Bacterial Expression System Protein Service

Prokaryotic protein expression system is the most common and economical protein expression method today, and the E. coli expression system is one of the most important and widely used prokaryotic protein expression systems.

Elabscience’s E. coli protein expression system service starts with their proprietary codon optimisation and protein analysis. The gene will then be synthesised and subcloned, with pET series vectors and integrate GST or MBP tags selected according to customer needs. There is also a tag removal service during the transformation and small test, multiple expression strains such as BL21 (DE3), T7 Express, Rosseta gami (DE3) plys, Shuffle T7B and BL21 Codon Plus (DE3) are provided. In addition, Elabscience offers an endotoxin removal service to meet your special requirements. You can order each service or any combination of these services according to the project plan.

Advantages of Elabscience's Bacterial Expression System Protein Service:

• Competitive price
• Short period
• Guaranteed Package: 1~5 mg of purified proteins.
• High-purity protein production: A variety of purification methods combined with protein purification system can customise purity ≥95%.
• One-stop service platform: Elabscience can take your project directly from gene synthesis to downstream activities including recombinant protein expression, antibody production, and assay development.

Labelling Service

Antibody/protein/peptide labelling technology marks some easily detected and highly sensitive substances on the special antigen/antibody molecules. These markers can better display the position and content of the antigen/antibody molecules in the immune response system through their own amplification effect.

Elabscience provides labelling services including fluorochrome labelling, biotin labelling and HRP labelling.

Service Features:

• Fast service: only 1-2 weeks to complete the entire process.
• Wide range of tagged species to meet various experimental needs.
• Complete labelling service with a high success rate.

Polyclonal Antibody Service

Unlike monoclonal antibodies, polyclonal antibodies correspond to multiple epitopes and tend to contain several immunoglobulin subtypes. They can be used as both primary and secondary antibodies in Westerns, ELISAs, and IHCs.
Elabscience provides polyclonal antibody services in mouse, rat, rabbit, and other species. Their polyclonal antibody packages include antigen design, peptide synthesis, immunisation, purification, ELISA test, and lyophilisation.

Advantages of Elabscience's Polyclonal Antibody Service:

• Mature technology system can provide efficient and quality service: Elabscience has a mature technology system and high experimental success rate to provide you with an efficient and quality service.
• Flexible service portfolio: Different host species (mouse, rat, and rabbit) and purification method (Protein A/G purification/ Antigen Affinity purification) are available for your research demands.
• Personalised experiment scheme: Elabscience's experienced antibody experts will design the personalised experiment scheme according to your specific requirements and applications.