The plant Euphorbia resinifera contains the most potent irritant known so far. It was isolated and identified as resiniferatoxin (RTX).
Resiniferatoxin (RTX) – Potent TRPV1 Agonist for Pain Relief
Manumycin A – Exosome Biogenesis Inhibitor
Manumycin A is an inhibitor of exosome biogenesis & secretion. Targeting exosome biogenesis could exert RAS signalling inhibitors’ anticancer effects.
Nano Vaccines Induce T Cell Immunity and Control of Tumour Growth
Using nanoparticle technology in making vaccines for infectious diseases/cancer is advancing & enhances the immunogenicity of some vaccine candidates.
Future Fields’ Fly-Based Growth Factors Earn Sustainable ACT Label from My Green Lab
Future Fields’ serum-free growth factors have achieved the ACT Environmental Impact Factor Label from My Green Lab.
Popular Targets for Bispecific Antibody Drugs
Bispecific Antibody drugs gained popularity since approval of blinatumomab. 6 bsAb drugs are approved by the US FDA/EMA & 180+ are in clinical trials.
Is your drug candidate able to reverse the T Cell Exhaustion-like state in MBL’s in vitro functional screening assay?
The process of T cell exhaustion & how it can be harnessed for immuno-oncology drug discovery and for immune checkpoint screening of drug candidates.