The PD-1 protein is a negative co-stimulatory receptor that can bind two different but related ligands, PD-L1 and PD-L2. Upon binding, signals generated by PD-1 inhibit the activation of the immune response in the absence of “danger signals.” ProSci Inc.
Validating the use of TransFix to stabilise cerebrospinal fluid (CSF) for flow cytometry immunophenotyping of haematological malignancies
Cytomark, a division of Caltag Medsystems, recently presented a scientific poster at the ICCS2017 conference in collaboration with Bristol Royal Infirmary (Bristol, UK) “Validating the use of TransFix to stabilise cerebrospinal fluid (CSF) for flow cytometry immunophenotyping of haematological malignancies”
Inter-laboratory Comparison of the TransFix/EDTA Vacuum Blood Collection Tube (TVT) with the 5 mL Cyto-Chex® BCT
Cytomark, a division of Caltag Medsystems, recently presented a scientific poster at the ICCS2017 conference in collaboration with the Royal Hallamshire Hospital (Sheffield, UK), Royal Sussex County Hospital (Brighton, UK), and Roswell Park Cancer Institute (Buffalo, NY, USA). “Inter-laboratory Comparison of the TransFix/EDTA
Reduce Variability in Clinical Trials by Stabilizing Samples
TransFix/EDTA Vacuum Blood Collection Tubes (TVTs) have been cleared for IVD use in the United States and Europe. Prefilled with TransFix and K3EDTA, these tubes allow for convenient collection, anticoagulation, and instant stabilization of peripheral blood for flow cytometric analysis.
Your Cell Line Provider
Looking for a certain cell line? AddexBio provides a variety of cell lines: cancer, immortalised, primary and stable cell lines for research studies. These cell lines can be used to improve our understanding of diseases. AddexBio only provide quality and
“Let’s Make America the Country That Cures Cancer Once and For All”
During the 2016 State of the Union Address, President Obama called attention to a myriad of issues currently plaguing Americans. One of the many initiatives President Obama announced in response was a “moonshot” to cure cancer, referencing the flood of
A Brief Introduction to PD-1 Antibodies and Immunotherapy
President Jimmy Carter’s cancer remission was wonderful news, but as some outlets [1] noted, it is important to understand that not all patients are responding as well to similar treatments, and that there is currently still no “cure” for cancer.
Blood Controls for Flow Cytometry
Routine haematological testing requires the use of reference material during machine set up such that validation prior to analysis of patient samples can be performed. Many also require repeat use of reference controls throughout the running period of the machine,
Cell Fixation and Permeabilistation Kit for Intracellular Staining
Intracellular staining of protein biomarkers using antibodies in flow cytometry has opened up a diversity of new options for phenotypic and functional characterisation of cells in both research and clinical diagnosis. Definitive phenotypic identification of certain cell types can require labelling
The Fas and the Furious 2: The Importance of Fas in Cancer
Given the prominent role of Fas in many important cell functions (Read: 7 Facts to Catch You Up to Speed on Fas). Fas has been implicated in a variety of disease states such as cancer. Here are some major findings