MBL International offers CD1d tetramers prepared by tetramerisation of complexes of CD1d and β2m by PE- or APC- labelled streptavidin.
CD1d Tetramers for Monitoring Invariant Natural Killer T (iNKT) cells
New B7 Family Immune Checkpoint Proteins
Recently 5 new B7 family ligands, B7-H3, B7-H4, B7-H5, B7-H6 & B7-H7, were identified, all of them possibly of high interest in immunotherapy research.
Is your drug candidate able to reverse the T Cell Exhaustion-like state in MBL’s in vitro functional screening assay?
The process of T cell exhaustion & how it can be harnessed for immuno-oncology drug discovery and for immune checkpoint screening of drug candidates.
Human MHC Class II QuickSwitch™ Platform is used to Identify SARS-CoV-2 Virus Derived Peptides
In a previous blog post (How to screen SARS-CoV-2 peptides to facilitate T cell research) MBL International described how the immune system samples all of the pathogenic proteins by looking at the small fragments of each protein and determining whether that
How to Identify SARS-CoV-2 Virus Derived Peptides
In a previous blog post (How to screen SARS-CoV-2 peptides to facilitate T cell research), MBL International describes how the immune system samples all of the pathogenic proteins by looking at the small fragments of each protein and determining whether
Find Human MHC Class I Dominant Peptides
In a previous blog post (How to screen SARS-CoV-2 peptides to facilitate T cell research) MBL International described how the immune system samples all of the pathogenic proteins by looking at the small fragments of each protein and determining whether
Comparing Theoretical Peptide-MHC Binding Affinity to Real Values produced by the QuickSwitch™ Platform
In a previous blog post (How to screen SARS-CoV-2 peptides to facilitate T cell research) MBL International described how the immune system samples all of the pathogenic proteins by looking at the small fragments of each protein and determining whether
How to screen SARS-CoV-2 peptides to facilitate T cell research
Whenever our immune system is faced with a challenge, be it a multicellular parasite, a bacteria, a virus, or even cancer, this threat is detected and sampled primarily by the protein sequence of the pathogen in question. Other aspects of
Interleukin-6 release in response to Coronavirus 19
Coronavirus 19 is known to infect the respiratory tract and cause mild or highly acute respiratory syndrome. A consequence of this is the release of pro-inflammatory cytokines, including interleukin (IL)-1β and IL-6 (1). This hyperinflammatory response is thought to be
Coronavirus (COVID-19) Research Tools
Recently, scientists have discovered a novel strain of Coronavirus (COVID-19) that is more deadly than SARS-CoV and MERS-CoV combined. This has caused a massive viral outbreak globally, and due to the lack of information about this strain, there are limited