In a previous blog post (How to screen SARS-CoV-2 peptides to facilitate T cell research) MBL International described how the immune system samples all of the pathogenic proteins by looking at the small fragments of each protein and determining whether
Comparing Theoretical Peptide-MHC Binding Affinity to Real Values produced by the QuickSwitch™ Platform
In a previous blog post (How to screen SARS-CoV-2 peptides to facilitate T cell research) MBL International described how the immune system samples all of the pathogenic proteins by looking at the small fragments of each protein and determining whether
Screening for COVID-19 T-Cell Peptides and Immune Monitoring with MHC Tetramers In A Single Assay
COVID-19 infected cells can be recognized by T-cells only after SARS-CoV-2 peptides are processed and presented in the context of self MHCs. Identifying these peptides have essential utilities: Immune monitoring: Using peptide-MHC tetramers to assess vaccine-induced immunity Designing potent vaccines
Interleukin-6 release in response to Coronavirus 19
Coronavirus 19 is known to infect the respiratory tract and cause mild or highly acute respiratory syndrome. A consequence of this is the release of pro-inflammatory cytokines, including interleukin (IL)-1β and IL-6 (1). This hyperinflammatory response is thought to be
Coronavirus (COVID-19) Research Tools
Recently, scientists have discovered a novel strain of Coronavirus (COVID-19) that is more deadly than SARS-CoV and MERS-CoV combined. This has caused a massive viral outbreak globally, and due to the lack of information about this strain, there are limited
A Summary of ProSci’s Research on HIV
ProSci‘s roots lie in the research of Human Immunodefficiency Virus and working to develop a neutralizing vaccine against it. Below is an “abstract of abstracts” summarizing the research performed over the last several years that has built their business from