T cell-dependent OVA antigen is used as a model protein for studying antigen-specific immune responses in mice. MBL has OVA related tetramer products.
Defined Immune Response Tracking in Mice: OVA MHC Tetramers
Streamline the detection of CD4 T cells with QuickSwitch™ Class II Quant Tetramer Kits
Use QuickSwitch™ Class II Quant Tetramer to investigate peptide-MHC binding affinities & conclude with your specialised CD4+ T cell detection reagent!
Protective Role of Invariant Natural Killer T (iNKT) cells
CD1d, non-classical MHC molecules, present phospholipid & glycosphingolipid antigens to iNKT cells. MBL tetramers help measure CD1d positive NKT cells
2023 Advancements in Research with QuickSwitch™ Custom Tetramer Kits
Here are the highlights of some of the influential publications that have utilised MBLI QuickSwitch™ Tetramer Kits in 2023.
Respiratory Syncytial Virus (RSV): Continued Research for the Most Prevalent Respiratory Virus Among Children
RSV is a significant respiratory virus in young children, & is the primary cause of hospitalisations, particularly bronchiolitis & pneumonia.
The invaluable role of QuickSwitch™ kits in validating predicted results
Wang, Wenfeng, et al 2023, selected the top 15 top peptides for self-antigen for their study. By using the QuickSwitch™ kit, they successfully switched 6 peptides to the tetramer complex with an efficiency of over 75%.
Ensure Accurate Immune Monitoring Results with Negative Controls
Negative controls aid precision of immune response monitoring. For HLA-A*02:01 alleles, MBLI offers a “Negative Tetramer” in BV421, PE or APC.
Validation of Neoantigen In Silico Prediction using QuickSwitch™ Kits
Research findings indicate that neoantigens have the potential to activate tumour-specific T-cell-mediated anti-tumour immune responses.
Tetramer Gating Strategy For True Positives Results
Investigators have developed a gating strategy that effectively minimises non-specific staining by incorporating a dump channel.
Correlation Between HLA Typing and Immune Monitoring in Human Disease
The human leukocyte antigen system, aka human major histocompatibility complex, was named after its discovery with alloantibodies against leukocytes.