Ever wonder how cholesterol levels are regulated? One of the major regulators is a molecule called proprotein convertase subtilisin/kexin type 9 or PCSK9 for short! PCSK9 has been implicated in causing hypercholesterolemia (high cholesterol), and diseases such as coronary heart
Stop Crying in the Lab: How Cry Antibodies Can Help Your Research
Tiredness and frustration often mount after long nights in the lab. Why can’t our bodies adjust and allow us to maintain our energy through the night? The answer lies in our circadian rhythms. Circadian rhythms are the daily cycle
Help! My mouse tetramer stained ALL the CD8+ T cells!
You’re sitting at your flow cytometer, staring at your CD8 x tetramer plot in anticipation of a tiny but meaningful group of dots appearing in the upper right quadrant. You hold your breath, click “acquire,” and watch… Wait, what? What’s
Colorimetric? Fluorometric? How to choose the right platform for your ELISA
What happens when you use a black well plate for a fluorometric ELISA assay reading? What happens when you use a clear well plate for a colorimetric ELISA assay reading? Well the short answer is that you made the right
Don’t FRET- You’ve got Fluoppi!
Visualizing protein-protein interaction (PPI) is pretty neat. You are able to glimpse into a really unique aspect of nature that many people don’t get to see. It’s like watching lions and zebras interact but without the bloody violence. However, anyone
Who’s that on my mRNA? RiboTrap Kit from MBLI
You have an RNA of interest aka your favorite RNA. The question is: which RBPs interact with it? Who are these RBPs and what are their intentions with your precious RNA? It’s not yet known how diseases are regulated or
Improve your RNA research using our anti-BrdU antibody!
How do you quantify newly synthesised RNA? There are several ways to detect synthesised RNA, but these methods have their complications. The 5-Bromouridine immunoprecipitation chase (BRIC) Kit offers the the most suitable method for RNA decay analysis. Regulation of gene expression by RNA degradation
Don’t rip your hair out- use our RIP certified antibodies!
What are RBPs (RNA binding proteins)? Very briefly, they are proteins that bind to RNA. (You probably figured that out already.) More importantly, they have a role in regulating RNA as part of the ribonucleoprotein complex (RNP). They are involved
Immunostaining of Circulating Tumour Cells in TransFix Stabilised Blood Samples
The presence of circulating tumour cells (CTC’s) has been shown to be of diagnostic relevance for patients with early and advanced breast cancer (BC). The usefulness of CTC assessments depends upon accurate cell counts and the corresponding analysis of molecular
Autophagy Watch
What does autophagy flux mean? You have come to the right place to learn a little more about autophagy flux and how MBL International’s Autophagy Watch kit can help you. Autophagy allows for cell survival during subprime conditions, such as nutrient