Inflammasomes are multi-protein complexes whose activity has been implicated in physiological and pathological inflammation. The hallmarks of inflammasome activation are the secretion of the mature forms of caspase-1 and interleukin-1β (IL-1β) from cells of the innate immune system. AdipoGen provides
The HitAlert Kit: A complete kit for the reliable diagnosis of Heparin-Induced Thrombocytopenia
The HITAlert Kit™ is a CE/IVD functional assay for the diagnosis of Heparin Induced Thrombocytopenia. This kit uses donor platelets (PRP) which are incubated in the presence of patient serum and in the presence or absence of heparin. A platelet activation marker
Can you solve our brainteaser?
Chuck caught himself an alligator in the swamp and took it over to Larry’s place to weigh it. It turned out that the tail alone weighed 80 pounds. The head weighed as much as the tail and half the body,
Tailored Media for Proliferation and ECM Production
Traditional fibroblast media utilise 10% serum combined with very simple basal media formulations. The new CnT-PR-F medium uses an advanced basal medium formulation and a mix of defined growth factors to reduce the serum requirement down to 1%. As a
Features of Melanocyte Differentiation Medium
Traditional melanocyte media contain a mixture of signals and aim to provide both strong proliferation, whilst maintaining melanin expression and dendricity. However, the cells do not receive such mixed signals in vivo and are unable to provide all these behaviours
Double Keratinocyte Isolation Efficiency with Isoboost
Isolation is a considerable stress for primary cells, in which the physical detachment and loss of cohesion results in significant loss of viability and reduced attachment. The new IsoBoost supplement (CnT-ISO-50) is able to significantly boost the isolation efficiency of primary
Blood Controls For Flow Cytometry – Samples Available
Cytomark are currently providing free samples of Stabilised Human Whole Blood and CD4 Low & Normal Blood Controls to all UK customers. These blood controls are available immediately for testing and have a 90 day sample stability. To request a sample,
Features of CnT Prime Medium
CnT-Prime is a fully defined medium, that is free of all human and animal-derived components. It uses an optimised basal medium with additional trace elements, protective antioxidants and vitamins. This basal medium is then supplemented with a range of Progenitor
Detection of human DJ-1/PARK7
The CircuLex Human DJ-1/PARK7 ELISA Kit has been developed to measure the concentration of human DJ-1/PARK7 from human serum, plasma, cell lines and conditioned media. DJ-1 (PARK7/CAP1/RS) is expressed in many cells and tissues, including the brain. Over-expression of DJ-1
Flagellin – A TLR5/NLRC4 Agonist
Toll-like receptor 5 (TLR5) recognises flagellin from both Gram-positive and Gram-negative bacteria. Activation of the receptor stimulates the production of proinflammatory cytokines, such as TNF-α, through signalling via the adapter proteins MyD88, TIRAP and TRIF. Flagellin is the subunit protein