Using CHP staining, researchers observed active collagen turnover in grafts, indicating that the ECM was being actively remodelled.
Understanding ECM Remodelling in Full-Thickness Skin Grafts: Insights from Collagen Hybridising Peptide Staining
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Using CHP staining, researchers observed active collagen turnover in grafts, indicating that the ECM was being actively remodelled.
Collagen Hybridising Peptides (CHPs) selectively bind to damaged collagen, allowing precise visualisation and quantification of IVD in tissue samples.
This paper explores conjugating CHPs to water-soluble N-(2-hydroxypropyl)methacrylamide (HPMA) copolymers for tumor targeting and drug delivery.
Collagen is the most abundant protein in the human body. It is a critical component of almost all organs and tissues, providing the framework for cell attachment and growth. Collagen degradation regulates normal tissue remodelling which occurs during development, homeostasis