Biomarker of dermatomyositis with rapidly progressive interstitial lung disease Clinically amyopathic dermatomyositis (CADM), dermatomyositis without muscle weakness, is associated with elevated rates of rapidly progressive interstitial lung disease (RP-ILD), which is extremely resistant to treatment. The prognosis is poor after
Inflammatory bowel disease (IBD), which affects millions of people worldwide, is made up of various conditions that cause chronic inflammation of the gastrointestinal (GI) tract. The two main conditions are ulcerative colitis and Crohn’s disease. Crohn’s disease can affect any
In a previous blog post (How to screen SARS-CoV-2 peptides to facilitate T cell research) MBL International described how the immune system samples all of the pathogenic proteins by looking at the small fragments of each protein and determining whether
In a previous blog post (How to screen SARS-CoV-2 peptides to facilitate T cell research) MBL International described how the immune system samples all of the pathogenic proteins by looking at the small fragments of each protein and determining whether
Whenever our immune system is faced with a challenge, be it a multicellular parasite, a bacteria, a virus, or even cancer, this threat is detected and sampled primarily by the protein sequence of the pathogen in question. Other aspects of
When someone contracts COVID-19, the host’s immune response can be measured by the presence of neutralising antibodies. Neutralising antibodies prevent the interaction between SARS-CoV-2 virus and receptors on human cells, giving the patient immunity. Neutralising antibody detection is therefore very
The process of autophagy was first recognized in the late 1950s and it was thought of as bulk “junk” removal. Then, dedicated scientists did a little more digging and found there is an amazing methodology to the “junk” removal. It
3D cell culture innovation ensures that time spent at the bench will correlate to in vivo environments, with possibilities to aid in future discoveries such as drug delivery into tumor cells or understanding tissue microenvironment. Typically, a researcher use a