The MHC Monomer is a sub-component of an MHC Tetramer. Biotinylated Monomers are available for most associated Tetramer products.
Why is the MHC monomer the ideal choice for your experimental design?
Cancer Immunotherapy: An increasing emphasis on CD4+ T cells and MHC Class II Neoantigens
QuickSwitch™ Class II Tetramer Peptide Exchange and Quantitation Kit utilises a patented technique for exchanging up to ten peptides on an MHC Class II Tetramer.
Tetramer Gating Strategy For True Positives Results
Investigators have developed a gating strategy that effectively minimises non-specific staining by incorporating a dump channel.
Correlation Between HLA Typing and Immune Monitoring in Human Disease
The human leukocyte antigen system, aka human major histocompatibility complex, was named after its discovery with alloantibodies against leukocytes.
Tips for Staining Rare Antigens with MHC Tetramers
When performing staining with MHC tetramers, there may be certain cases where the staining is unclear. An example could be in certain cases where an antigen-specific T cell population of interest has a low frequency. The following tips discussed in