China Perform First Injection of CRISPR Modified Cells into a Person Use of CRISPR-Cas9 in human cells for treatment of disease has been a controversial topic amongst scientists since the discovery of the powerful gene editing tool. In this clinical
Bacterial vs. Mammalian Expression Systems
Expressing recombinant antibodies can be done in all kinds of systems. Many different cell lines can be used for expressing antibodies, including mammalian cells like HEK293 or CHO, or even yeast, plant or insect cell lines. Each expression system has
October 2016: The Antibody Update
The Nobel Prize in Medicine was Awarded to Yoshinori Ohsumi for His Work on Autophagy Autophagy is the cellular process that regulates a cells ability to degrade parts of itself that must be replaced. Yoshinori Ohsumi’s work in autophagy has proven to
Antibody Basics: Recombinant Antibodies
Antibody development works much like any engineering feat; you get out what you put in. With the shotgun approach to developing polyclonal antibodies, hitting the target usually isn’t too much of a problem, but the immune response can be nonspecific.
The Antibody Basics Series: Table of Contents
ProSci’s the Antibody Basics are a planned series of blogs designed to teach the science behind antibody development, and to serve as a buyers guide to assure that we develop the perfect product for your project. Not too long ago,
September 2016: The Antibody Update From ProSci
ProSci’s top news picks for September 2016 include a paper on a novel monoclonal antibody against parenchymal amyloid-beta for the treatment of Alzheimer’s Dementia, a scientist using CRISPR for gene editing of embryos, and an update on the discussion of
Antibody Basics: Isotypes
Antibodies come in several shapes and sizes, leading to a variance in properties and purposes. Below is a broad outline of each of the major isotypes of antibodies and how they are used. Some isotypes can be isolated incredibly easily
August 2016: The Antibody Update from ProSci
ProSci’s top news picks for August 2016 include a study on T-cell activity inside tumor tissue, the potential effects of Zika virus in adults, and mRNA therapeutics. T-cells Run
A Summary of ProSci’s Research on HIV
ProSci‘s roots lie in the research of Human Immunodefficiency Virus and working to develop a neutralizing vaccine against it. Below is an “abstract of abstracts” summarizing the research performed over the last several years that has built their business from
July 2016: The Antibody Update from ProSci
This months ProSci Antibody Update’s news includes the discovery of a new MRSA antibiotic found in the nose, the newest map of the human brain, and the discovery of a neutralizing antibody against the highly conserved HA stalk of inluenza.