The MHC Monomer is a sub-component of an MHC Tetramer. Biotinylated Monomers are available for most associated Tetramer products.
Flexibility and Expansion with BV421 Tetramers
Adding another marker to a flow cytometry panel can present a challenge when trying to accommodate all markers of interest in one panel. However, there is a solution.
QuickSwitch™ Quant Analysis of SARS-CoV-2 mRNA Vaccinations
MBL International provides QuickSwitch™ Tetramers for the Quant Analysis of SARS-CoV-2 mRNA Vaccinations.
Rapid and Reliable Custom Tetramer Generation for T-Cell Staining
MBLI QuickSwitch™ kit technology aims to replicate the immune response by mimicking peptide exchange on an MHC molecule.
Streamline the detection of CD4 T cells with QuickSwitch™ Class II Quant Tetramer Kits
Use QuickSwitch™ Class II Quant Tetramer to investigate peptide-MHC binding affinities & conclude with your specialised CD4+ T cell detection reagent!
Protective Role of Invariant Natural Killer T (iNKT) cells
CD1d, non-classical MHC molecules, present phospholipid & glycosphingolipid antigens to iNKT cells. MBL tetramers help measure CD1d positive NKT cells
2023 Advancements in Research with QuickSwitch™ Custom Tetramer Kits
Here are the highlights of some of the influential publications that have utilised MBLI QuickSwitch™ Tetramer Kits in 2023.
What Exactly is a TCR Tetramer?
A TCR Tetramer is a reagent prepared by tetramerising biotinylated antigen-specific TCRs with the help of phycobiliprotein-labelled streptavidin.
The invaluable role of QuickSwitch™ kits in validating predicted results
Wang, Wenfeng, et al 2023, selected the top 15 top peptides for self-antigen for their study. By using the QuickSwitch™ kit, they successfully switched 6 peptides to the tetramer complex with an efficiency of over 75%.
Ensure Accurate Immune Monitoring Results with Negative Controls
Negative controls aid precision of immune response monitoring. For HLA-A*02:01 alleles, MBLI offers a “Negative Tetramer” in BV421, PE or APC.