NSJ Bioreagents

LGALS13 Antibody / Galectin 13

Product Code:
 
NSJ-V5623
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Mouse
Antibody Isotype:
 
Mouse IgG2b, kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
PP13/8897
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Immunohistochemistry- Paraffin Embedded (IHC-P)
Storage:
 
Aliquot the Galectin 13 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
1 / 2
IHC staining of FFPE human placental tissue with Galectin-13 antibody (clone PP13/8897). Inset: PBS used in place of primary Ab (secondary Ab negative control). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
2 / 2
SDS-PAGE analysis of purified, BSA-free Galectin-13 antibody (clone PP13/8897) as confirmation of purity and integrity of antibody.
❮❯

IHC staining of FFPE human placental tissue with Galectin-13 antibody (clone PP13/8897). Inset: PBS used in place of primary Ab (secondary Ab negative control). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
SDS-PAGE analysis of purified, BSA-free Galectin-13 antibody (clone PP13/8897) as confirmation of purity and integrity of antibody.

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CodeSizePrice
NSJ-V5623-20UG20 ug£264.00
Quantity:
NSJ-V5623-100UG100 ug£534.00
Quantity:
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Further Information

Application Details:
Immunohistochemistry (FFPE): 1-2ug/ml
Application Note:
Optimal dilution of the Galectin 13 antibody should be determined by the researcher.
Description:
It recognizes a 32kDa protein, which is identified as homodimer of galectin-13 (also known as PP13). Galectins are a family of soluble beta-galactoside-binding lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. One such member, galectin-13, is a 139 amino acid protein that contains one galectin domain. Possessing lysophospholipase activity, galectin-13 exists as a disulfide-linked homodimer. Galectin-13 is suggested to have a developmental role in the placenta and may display immunobiological activity in feto-maternal blood-spaces. Screening for galectin-13 in maternal serum during the first trimester of pregnancy may serve as a diagnostic marker to predict preterm pre-eclampsia.
Format:
Purified
Formulation:
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Immunogen:
A recombinant human Galectin-13 protein fragment (amino acids 1-139) was used as the immunogen for the Galectin 13 antibody.
Limitation:
This Galectin 13 antibody is available for research use only.
Localisation:
Cytoplasm, Cell membrane
Purity:
Protein A/G affinity
Uniprot #:
Q9UHV8